How to Pronounce Amyotrophic Lateral Sclerosis
Definition, meaning, and phonetic spelling
Amyotrophic Lateral Sclerosis Pronunciation
ay-my-oh-TROH-fik LAT-er-al skleh-ROH-sis
Stressed syllable in ALL CAPS · hyphens separate syllables
Syllable Breakdown
ay
my
oh
TROH
stress here
fik LAT
er
al skleh
ROH
stress here
sis
9 syllables
What is Amyotrophic Lateral Sclerosis?
Amyotrophic lateral sclerosis (ALS) is a nervous system disease that attacks nerve cells called neurons in your brain and spinal cord. These neurons transmit messages ...
Definition sourced from MedlinePlus, National Library of Medicine
Questions About Amyotrophic Lateral Sclerosis
How do you pronounce 'Amyotrophic Lateral Sclerosis'?
+
Say it like this: ay-my-oh-TROH-fik LAT-er-al skleh-ROH-sis. Break it into four parts: the first part sounds like "ay-my-oh," the second part is stressed and sounds like "TROH-fik," the third part is "LAT-er-al," and the fourth part ends with "skleh-ROH-sis." The biggest stress falls on the TROH syllable in the second part.
What's the correct way to break this word into syllables?
+
Amyotrophic Lateral Sclerosis breaks down like this: a-my-o-TROPH-ic LAT-er-al scler-O-sis. It's a long word with 11 syllables total, so taking it slowly piece by piece makes it easier to say correctly.
What's the most common mispronunciation of this word?
+
Many people stress the wrong syllable and say "am-ee-oh-TROP-ic" instead of putting the emphasis on the TROH part. Others rush through it too quickly and slur the syllables together. Slow down and remember that TROH gets the strong stress to say it correctly.
What do the word parts 'amyo,' 'trophic,' and 'sclerosis' actually mean?
+
These are Greek and Latin roots: "amyo" means muscle, "trophic" comes from a Greek word meaning nourishment or growth, and "sclerosis" means hardening or scarring. Put together, the name describes a condition affecting muscle nutrition and nerve hardening.
What's the short form or abbreviation for this condition?
+
The most common abbreviation is ALS, which you pronounce by saying each letter: A-L-S. You might also hear it called "Lou Gehrig's disease" after a famous baseball player, but ALS is the standard medical shorthand used by doctors and in hospitals.
What does 'Amyotrophic Lateral Sclerosis' mean in everyday English?
+
In plain terms, it describes a disease where muscles waste away because the nerves that control them are damaged. The word "amyotrophic" literally means "without muscle nourishment," and "lateral sclerosis" refers to hardening on the sides of the spinal cord where the damaged nerves are located.
Are there other medical words that share the root 'sclerosis'?
+
Yes! You'll hear "sclerosis" in other medical terms like "multiple sclerosis" (MS) and "arteriosclerosis" (hardening of arteries). The root word always refers to some kind of hardening or stiffening in the body, so recognizing "sclerosis" helps you understand what these conditions have in common.
Can you use this word in a simple sentence?
+
Here's an example: "The doctor explained that Amyotrophic Lateral Sclerosis is often called ALS for short." Or: "Her family learned about Amyotrophic Lateral Sclerosis after her diagnosis." Using the full name shows you understand the formal medical term, while ALS works fine in casual conversation.

