How to Pronounce Hurler Syndrome
Definition, meaning, and phonetic spelling
Hurler Syndrome Pronunciation
HUR-ler SIN-drohm
Stressed syllable in ALL CAPS · hyphens separate syllables
Syllable Breakdown
HUR
stress here
ler SIN
drohm
3 syllables
What is Hurler Syndrome?
The most severe form of mucopolysaccharidosis type I (MPS I), caused by deficiency of the enzyme alpha-L-iduronidase, leading to accumulation of glycosaminoglycans in cells and tissues throughout the body. It causes progressive cognitive decline, skeletal deformities, cardiac disease, and multi-organ failure, and can involve the bone marrow; early bone marrow transplant can slow neurological progression.
Questions About Hurler Syndrome
How do you pronounce 'Hurler Syndrome'?
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Hurler Syndrome is pronounced HUR-ler SIN-drohm. The first word rhymes with 'curler' (the hair tool), and the second word sounds like 'syndrome.' Say it as two separate words, with the stress on the first syllable of each: HUR and SIN.
Which syllable gets the stress in 'Hurler Syndrome'?
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The stress falls on the first syllable of each word: HUR-ler and SIN-drohm. A common mistake is stressing the second syllable and saying hur-LER, but the correct way is to emphasize HUR at the beginning.
How do you break 'Hurler Syndrome' into syllables?
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Hurler breaks into two syllables: HUR-ler. Syndrome breaks into two syllables: SIN-drohm. Together they form four syllables: HUR-ler SIN-drohm.
What does the word 'syndrome' mean?
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Syndrome means a group of signs or features that happen together and identify a particular condition. The word comes from Greek roots meaning 'running together.' In medical terms, it simply tells you that multiple related characteristics appear as a package.
Where does the name 'Hurler' come from?
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Hurler Syndrome is named after Gertrude Hurler, an Austrian pediatrician who first described this condition in 1919. Like many diseases, it was named after the doctor who identified it, which is why you'll see the doctor's last name capitalized in the term.
What is the abbreviation for Hurler Syndrome?
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Hurler Syndrome is often abbreviated as MPS I or MPS-I, which stands for mucopolysaccharidosis type one. You would say this as 'em-pee-ess type one' or just spell out the letters individually.
What is a plain English way to understand what 'Hurler Syndrome' means?
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Hurler Syndrome is a rare genetic condition where the body cannot break down certain substances properly, causing them to build up in cells and tissues over time. This buildup affects multiple parts of the body and causes a group of ongoing changes.
How would you use 'Hurler Syndrome' in a sentence?
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You might hear it used like this: 'The patient was referred to a genetic specialist because Hurler Syndrome was suspected.' Or: 'Researchers are studying new approaches for Hurler Syndrome because it affects multiple organ systems.'