How to Pronounce MELAS Syndrome
Definition, meaning, and phonetic spelling
MELAS Syndrome Pronunciation
MEE-las SIN-drohm
Stressed syllable in ALL CAPS · hyphens separate syllables
Syllable Breakdown
MEE
stress here
las SIN
drohm
3 syllables
What is MELAS Syndrome?
A mitochondrial disorder whose acronym stands for Mitochondrial Encephalomyopathy, Lactic Acidosis, and Stroke-like episodes, most often caused by the m.3243A>G mutation in mitochondrial DNA. It typically presents in children or young adults with recurrent stroke-like episodes causing sudden weakness or vision loss, seizures, dementia, hearing loss, and elevated blood lactate.
Questions About MELAS Syndrome
How do you pronounce MELAS syndrome?
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MELAS syndrome is pronounced "MEE-las SIN-drohm." The first part rhymes with "fee" and "bee," and the second part sounds like "sin" (as in mistake) plus "drome" (rhymes with "home"). The stress falls on the first syllable: MEE-las.
What does the abbreviation MELAS actually stand for?
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MELAS is short for Mitochondrial Encephalomyopathy, Lactic Acidosis, and Stroke-like episodes. Each letter in the acronym represents the start of one of these longer medical words. When doctors use "MELAS," they're using a shorthand way to refer to the whole condition without saying all four long words.
How do you break MELAS syndrome into syllables?
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MELAS syndrome breaks into four syllables: MEE-las SIN-drohm. The word "MELAS" has two syllables (MEE-las), and "syndrome" has two syllables (SIN-drohm). The biggest stress is on the very first syllable, MEE.
What is a common mistake people make when saying MELAS?
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A common mistake is pronouncing it "MEL-us" (rhyming with "jelly") instead of "MEE-las." Remember: the first syllable should sound like the word "me," not "mel." It's MEE-las, not MEL-us.
What does the word 'syndrome' mean in medical language?
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Syndrome means a group of symptoms or signs that happen together and form a recognizable pattern or condition. It comes from Greek and means "running together." When doctors say "syndrome," they're talking about several things that go together as one condition.
What are the word parts in 'mitochondrial'?
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Mitochondrial comes from Greek roots: "mito-" means thread, and "-chondrion" means grain or granule. Scientists named mitochondria (the plural form) "thread-like granules" because they look like tiny threads under early microscopes. Mitochondrial just means "relating to the mitochondria."
Can you use MELAS in a sentence?
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Here's an example: "The doctor explained that MELAS syndrome is a rare genetic condition involving the mitochondria." You can say the full name "MELAS syndrome" or just "MELAS" when the context is clear.
Is it 'MELAS syndrome' or just 'MELAS'?
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Both are correct and used interchangeably. "MELAS syndrome" is the full, more formal way to say it. "MELAS" alone is a shorter, common way that doctors and people use when discussing the condition. Either form is acceptable.

