How to Pronounce Sister Mary Joseph Nodule
Definition, meaning, and phonetic spelling
Sister Mary Joseph Nodule Pronunciation
SIS-ter MAIR-ee JOH-sef NOD-yool
Stressed syllable in ALL CAPS · hyphens separate syllables
Syllable Breakdown
SIS
stress here
ter MAIR
ee JOH
sef NOD
yool
5 syllables
What is Sister Mary Joseph Nodule?
A firm, hard nodule at the umbilicus (belly button) caused by metastatic cancer from intra-abdominal or pelvic malignancies, most commonly gastric, ovarian, or colorectal cancer. Its presence is a sign of advanced, disseminated disease with poor prognosis.
Questions About Sister Mary Joseph Nodule
How do you pronounce 'Sister Mary Joseph Nodule'?
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Say it like this: SIS-ter MAIR-ee JOH-sef NOD-yool. The first word rhymes with 'blister,' the second and third names are pronounced like the common names Mary and Joseph, and the last word sounds like 'nod' plus 'yool' stuck together.
Which syllable gets the stress when you say this term?
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The stress falls on the first syllable of the first word: SIS-ter. People sometimes accidentally stress 'Joseph' instead, but the correct way is to emphasize SIS right at the beginning.
Why does this medical term have people's names in it?
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The term is named after Sister Mary Joseph, a nun who worked at Mayo Clinic in the early 1900s and noticed a pattern linking a certain belly button finding to internal cancer. Medical terms are often named after the doctors or healthcare workers who first described or studied them.
What does 'nodule' mean in 'Sister Mary Joseph Nodule'?
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A nodule is a small, firm lump or bump. In this phrase, it specifically refers to a hard bump that appears at the umbilicus, which is the medical word for your belly button.
How do you break 'Sister Mary Joseph Nodule' into syllables?
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Break it like this: SIS-ter / MAIR-ee / JOH-sef / NOD-yool. That's four parts total—one for each word in the phrase.
What is the plain English meaning of 'Sister Mary Joseph Nodule'?
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It means a hard bump at the belly button that is caused by advanced cancer spread from inside the body. It's a way doctors describe this specific finding they can see and feel.
Is there a shorter way to refer to this term?
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Yes, doctors sometimes just call it a 'Sister Mary Joseph node' or shorten it even further to 'SMJ nodule,' but these are less common in everyday medical language than saying the full name.
What is 'umbilicus' and how does it relate to this term?
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Umbilicus is the medical word for your belly button. The Sister Mary Joseph Nodule appears specifically at the umbilicus, so knowing this word helps you understand exactly where on your body this finding occurs.

