How to Pronounce Skyrizi

Definition, meaning, and phonetic spelling

Skyrizi Pronunciation

sky-RIZ-ee

Stressed syllable in ALL CAPS · hyphens separate syllables

Syllable Breakdown

sky

RIZ

stress here

3 syllables

What is Skyrizi?

Skyrizi (risankizumab) is a prescription injectable biologic medication used to treat moderate to severe plaque psoriasis, psoriatic arthritis, and moderate to severe Crohn's disease and ulcerative colitis in adults. It belongs to the drug class of interleukin-23 (IL-23) inhibitors, specifically blocking the p19 subunit of IL-23, a cytokine that plays a central role in chronic inflammatory conditions. Skyrizi is manufactured by AbbVie and has demonstrated high skin clearance rates in psoriasis and sustained remission in inflammatory bowel disease clinical trials.

Definition sourced from MedlinePlus, National Library of Medicine

Questions About Skyrizi

How do you pronounce Skyrizi?

Skyrizi is pronounced "sky-RIZ-ee." The stress falls on the second syllable (RIZ), so you say it a bit like "sky" (rhymes with "pie") + "RIZ" (rhymes with "fizz") + "ee" (like the letter E). The first syllable is said quickly and lightly, then you emphasize the middle syllable.

How many syllables does Skyrizi have?

Skyrizi has three syllables: sky-RIZ-ee. When you say it out loud, you can count three distinct beats or chunks to the word.

Which syllable in Skyrizi is stressed?

The second syllable—RIZ—is the stressed syllable in Skyrizi. This means you say it a little louder and hold it slightly longer than the first and third syllables, so it sounds like sky-**RIZ**-ee.

What is a common mispronunciation of Skyrizi?

A common mistake is stressing the first syllable and saying "**SKY**-ri-zee," but that's incorrect. Remember that the stress belongs on the middle syllable: sky-**RIZ**-ee. Another error is pronouncing the end like "zee" (the letter Z) instead of a soft "ee" sound.

Can you use Skyrizi in a sentence?

Sure! Here's an example: "The patient's doctor discussed whether Skyrizi might be a treatment option for their condition." This shows how you'd use the word in everyday medical conversation without giving any medical advice.

Is Skyrizi a brand name or generic name?

Skyrizi is a brand name (the trade name given by the manufacturer). The generic name—the scientific chemical name—is risankizumab, which is much longer and harder to say. Most people refer to this medication by its brand name, Skyrizi.

How would you spell out the pronunciation of Skyrizi for someone?

You can spell it out as: S-K-Y (like the sky), then R-I-Z (like fizz), then E-E (like the letter E twice). Put the emphasis on the RIZ part in the middle: sky-**RIZ**-ee.